摘要: 目的 了解青海省2009-2014年布鲁氏菌病（布病）的流行现状。 方法 对青海省2个市2个区18个县的布病进行调查分析。 结果 共调查24 831人，2009-2014年年平均感染率依次为5.30%、6.43%、5.76%、2.78%、3.09%和3.95%；年患病率依次为2.74%、2.35%、2.25%、0.87%、1.39%和2.21%。虎红平板凝集试验6年合计阳性率为4.16%（1 032/24 831），试管凝集试验平均阳性率为1.71%（425/24 831），抗人球蛋白试验平均阳性率为2.04%（21/1 027）。确诊布病新发病例316例，年发病率持续上升。布病病例主要集中在河南、天峻、共和、久治、达日县等饲养或屠宰牲畜地。发病区域依次为牧业区（238例）、城镇（43例）、农业区（31例）和半农半牧区（4例）。 结论 青海省布病疫情比较活跃，有蔓延趋势。

Abstract: Objective To comprehend the epidemiological trend of human Brucellosis in Qinghai province in 2009-2014. Methods Analyzed the investigation results of human Brucellosis in 2 cities, 2 districts and 18 counties in Qinghai province during 2009 to 2014. Results In 2009-2014, we investigated 24 831 humans, the annual infection rate were, in order, 5.30%, 6.43%, 5.76%, 2.78%, 3.09%, and 3.95%. The annual prevalence rate was, in order, 2.74%, 2.35%, 2.25%, 0.87%, 1.39%, and 2.21%. The average positive rate of RBPT was 4.16%(1 032/24 831), SAT was 1.71%(425/24 831), Coombs was 2.04%(21/1 027). Newly diagnosed cases were 316, each year's annual incidence was rising, results were statistically significant(χ²=66.505, P < 0.01). The cases were mainly concentrated in Henan, Tianjun, Gonghe, Jiuzhi, Dari county and other breeding and slaughtering animals based grassland farming counties. The number of cases were, in order, pastoral region(238), towns(43), agriculture region(31), farming-pastoral region(4). Conclusion Prevalence of human Brucellosis in Qinghai province is active with spreading tendency.